COVID-19 has changed everything. I’ve become a 6th and 4th grade teacher on top of being a PI. My students, postdocs, and staff have carefully navigated social distancing rules to do a much reduced number of experiments, but have made up for time lost in lab by writing grants and…
Today, Feb. 28th, the BLM helped celebrate Rare Disease Day. Russell Mellen presented his work to develop an AAV-CRISPR/Cas9- based approach for a pediatric retinal disease, cone-rod dystrophy. Dr. Kaitlyn Calabro presented her work to develop a dual AAV vector-mediated therapy for MYO7A Usher syndrome. We also took…
On February 25th, Dr. Calabro showed what being a good scientist is all about. She served as a guest lecturer at P.K. Yonge elementary school where she taught the kiddos (including Brett Looney’s son!) what it meant to be a scientist. Here she is showing them how cool you…
It wouldn’t be a BLM Christmas party without an epic White Elephant gift exchange. This year’s winners- my new Danny Devito pillow and Russell’s fashionable shirt. Love you crazy kids!…
Kaitlyn Calabro successfully defended her Ph.D. thesis on October 24th, 2019. Every student stands out for a particular reason. For Kait, it was her height (or lack thereof!), and her incredible work ethic. I knew from the first week of her lab rotation that she had enough elbow grease to…
After an exceptional 5 years as a postdoc in the Boye Lab, Shreyasi decided to get a ‘real job’ at Spark Therapeutics. We are lost without her super sweet voice announcing lab meeting every Friday! We’ll miss you Shreyasi and wish you all the best in your new endeavor!…
K. Tyler McCullough successfully defended his Ph.D. thesis on March 25th, 2019! We are excited that Tyler decided to join grad school (aka come to the ‘dark side’), and to conduct his studies in the Boye Lab. For the experience he brought with him, he was the program’s first ‘fast-track’…
Congratulations to Sean Crosson, Ph.D., Kaitlyn Calabro, and Russell Mellen for giving outstanding presentations at this year’s ASGCT meeting in Washington D.C.! Along with Dr. Boye, they rounded out 4 oral presentations at this year’s conference. Dr. Boye discussed her team’s efforts to develop novel AAV capsids that exhibit…
As if loving what you do for a living wasn’t enough, today I received a beautiful bouquet of flowers from a grateful patient all the way in Denmark. Thank you so much to Klaus and little Rasmus for this incredibly generous and unexpected surprise! This happens so infrequently in…
Genome-editing technologies that correct specific mutations represent a transformative new approach for treating genetic disorders. Despite its widespread use in mouse models of disease, and in cell lines, the Boye lab was the first to demonstrate the effects of CRISPR/Cas9 mediated gene editing in somatic cells of non-human primate. Their…
