Peer Reviewed Manuscripts
- Gamlin PD, Alexander JJ, Boye SL, Witherspoon CD, Boye SE. SubILM Injection of AAV for Gene Delivery to the Retina. Methods Mol Biol. 2019;1950:249–262. doi:10.1007/978-1-4939-9139-6_14
- McCullough KT, Boye SL, Fajardo D, et al. Somatic Gene Editing of GUCY2D by AAV-CRISPR/Cas9 Alters Retinal Structure and Function in Mouse and Macaque. Hum Gene Ther. 2019;30(5):571–589. doi:10.1089/hum.2018.193
- Calabro KR, Boye SL, Choudhury S, et al. A Novel Mouse Model of MYO7A USH1B Reveals Auditory and Visual System Haploinsufficiencies. Front Neurosci. 2019;13:1255. Published 2019 Nov 22. doi:10.3389/fnins.2019.01255
- Santiago CP, Keuthan CJ, Boye SL, Boye SE, Imam AA, Ash JD. A Drug-Tunable Gene Therapy for Broad-Spectrum Protection against Retinal Degeneration. Mol Ther. 2018;26(10):2407–2417. doi:10.1016/j.ymthe.2018.07.016
- Gamlin PD, Alexander JJ, Boye SL, Witherspoon CD, Boye SE. SubILM Injection of AAV for Gene Delivery to the Retina. Methods Mol Biol. 2019;1950:249–262. doi:10.1007/978-1-4939-9139-6_14
- Kanaan NM, Sellnow RC, Boye SL, et al. Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS. Mol Ther Nucleic Acids. 2017;8:184–197. doi:10.1016/j.omtn.2017.06.011
- Beltran WA, Cideciyan AV, Boye SE, et al. Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations. Mol Ther. 2017;25(8):1866–1880. doi:10.1016/j.ymthe.2017.05.004
- Jacobson SG, Cideciyan AV, Sumaroka A, et al. Defining Outcomes for Clinical Trials of Leber Congenital Amaurosis Caused by GUCY2D Mutations. Am J Ophthalmol. 2017;177:44–57. doi:10.1016/j.ajo.2017.02.003
- Boye SE. Increased vulnerability of photoreceptors to aberrant splicing highlight the utility of AON-based therapy for CEP290-LCA. Stem Cell Investig. 2016;3:96. Published 2016 Dec 27. doi:10.21037/sci.2016.12.01
- Choudhury S, Strang CE, Alexander JJ, et al. Novel Methodology for Creating Macaque Retinas with Sortable Photoreceptors and Ganglion Cells. Front Neurosci. 2016;10:551. Published 2016 Dec 1. doi:10.3389/fnins.2016.00551
- Xie K, Colgan LA, Dao MT, et al. NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum. Curr Biol. 2016;26(22):2992–3003. doi:10.1016/j.cub.2016.09.010
- Boye SL, Olshevskaya EV, Peshenko IV, McCullough KT, Boye SE, Dizhoor AM. Functional study of two biochemically unusual mutations in GUCY2D Leber congenital amaurosis expressed via adenoassociated virus vector in mouse retinas. Mol Vis. 2016;22:1342–1351. Published 2016 Nov 10.
- Boye SE, Alexander JJ, Witherspoon CD, et al. Highly Efficient Delivery of Adeno-Associated Viral Vectors to the Primate Retina. Hum Gene Ther. 2016;27(8):580–597. doi:10.1089/hum.2016.085
- Boyd RF, Boye SL, Conlon TJ, et al. Reduced retinal transduction and enhanced transgene-directed immunogenicity with intravitreal delivery of rAAV following posterior vitrectomy in dogs. Gene Ther. 2016;23(6):548–556. doi:10.1038/gt.2016.31
- Boye SL, Bennett A, Scalabrino ML, et al. Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors. J Virol. 2016;90(8):4215–4231. Published 2016 Mar 28. doi:10.1128/JVI.00200-16
- Ildefonso CJ, Jaime H, Brown EE, et al. Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide. Invest Ophthalmol Vis Sci. 2016;57(2):372–386. doi:10.1167/iovs.15-17703
- Ye GJ, Budzynski E, Sonnentag P, et al. Cone-Specific Promoters for Gene Therapy of Achromatopsia and Other Retinal Diseases. Hum Gene Ther. 2016;27(1):72–82. doi:10.1089/hum.2015.130
- Boyd RF, Sledge DG, Boye SL, et al. Photoreceptor-targeted gene delivery using intravitreally administered AAV vectors in dogs [published correction appears in Gene Ther. 2016 Apr;23(4):400]. Gene Ther. 2016;23(2):223–230. doi:10.1038/gt.2015.96
- Boye SE. A Mini-review: Animal Models of GUCY2D Leber Congenital Amaurosis (LCA1). Adv Exp Med Biol. 2016;854:253–258. doi:10.1007/978-3-319-17121-0_34
Book Chapters
- Title: Retinal Disorders: Genetic Approaches to Diagnosis and Treatment Editors: Eric Pierce, Richard Masland, Joan Miller Publisher: Cold Spring Harbor Press Chapter Title: Leber congenital amaurosis due to mutations in GUCY2D Author: Shannon E. Boye 2013
- Title: A Guide to Human Gene Therapy Editors: Herzog and Zolotukhin Publisher: World Scientific Chapter Title: Retinal Diseases Authors: Shannon E Boye, Sanford L Boye, William W. Hauswirth 2009
- Title: Mouse Visual System Editors: Chalupa and Williams Publisher: MIT Press Chapter Title: AAV Gene Therapy in Mouse Models of Retinal Degeneration Authors: SE Boye , SL Boye, WW Hauswirth 2008
- Title: Regenerative Medicine Editors: Robert C. Fisher and Edward W. Scott Publisher: Jones and Bartlett Chapter Title: Retina Authors: Hilda Petrs-Silva, Shannon Boye and William W. Hauswirth
Collections Edited
- Frontiers in Neuroscience “Ocular Gene Therapy: From Basic Research to Translational Studies” Editors: Shannon E. Boye, Stylianos Michalakis, Simon Petersen-Jones, Hildegard Büning. Collection in process 2015-2017
Other
- Sanford L. Boye and Shannon E. Boye. “Genetic Therapies for Inherited Retinal Disease”. Invited submission to ‘Retinal Physician’ magazine (peer reviewed). Published 5-1-15